Staging and Risk Stratification of Germ-Cell Tumors

Germ cell tumours of the testis are the commonest malignancy in men aged 20-40 years. Considerable therapeutic improvements in management—based on the cancer’s responsiveness to chemotherapy that contains platinum—mean that over 95% of these patients can now expect to be cured.
Continue reading

Summary of the ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce ASCVD

The updated American College of Cardiology/American Heart Association (ACC/AHA) Guideline on the Treatment of Blood Cholesterol (GTBC) has been long-awaited since the latest update of the Adult Treatment Panel III (ATP III) guidelines in 2004. The updated GTBC recommends a significant paradigm shift in lipid-loweringdrug therapy for atherosclerotic cardiovascular disease (ASCVD) risk reduction, which has led to questions regarding their content and their implementation.
Continue reading

Risk Factors for Contrast-Induced Nephropathy (CIN)

Contrast-induced nephropathy (CIN) is defined as the impairment of renal function and is measured as either a 25% increase in serum creatinine (SCr) from baseline or 0.5 mg/dL (44 umol/L) increase in absolute value, within 48-72 hours of intravenous contrast administration. Continue reading

MASCC Index Score for Identifying Low-Risk Febrile Neutropenic Cancer Patients

Scoring system for risk of complications among febrile neutropenic patients, based on the Multinational Association for Supportive Care in Cancer (MASCC) predictive model.

Continue reading

Clinical and Laboratory "Low Risk" Criteria for Children Younger Than 3 Months with Fever and No Focus of Infection

Clinical criteria

  • Born at term (gestational age >/= 37 weeks)with uncomplicated nursery stay
  • Previously healthy infants
  • Notoxic manifestations
  • No focal bacterial infection (except otitis media) Continue reading