ILAR Classification Criteria for Juvenile Idiopathic Arthritis (JIA)

Juvenile idiopathic arthritis is a heterogeneous group of diseases characterised by arthritis of unknown origin with onset before age of 16 years.
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The 2008 ACR Recommendations for Rheumatoid Arthritis Treatments

  • Initiating treatment with methotrexate or Arava (leflunomide) was recommended for most rheumatoid arthritis patients.
  • Methotrexate plus Plaquenil (hydroxychloroquine) was recommended for rheumatoid arthritis patients with moderate to high disease activity.

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Criteria for the Classification of Wegener's Granulomatosis (WG)

Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a rare form of vasculitis. In this disorder, small-sized blood vessels in the nose, sinuses, ears, lungs and kidneys become inflamed and damaged. Continue reading

Diagnostic Criteria for Thromboangiitis Obliterans (Buerger’s Disease)

Since specificity of Buerger’s disease is characterized by peripheral ischemia of an inflammatory nature and with a self-limiting course, diagnostic criteria should be discussed from clinical of view.

Several different criteria have been proposed for the diagnosis of thromboangiitis obliterans:

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Criteria for Diagnosis of Still's Disease

Yamaguchi criteria for classification of adult Still’s disease
Presence of 5 or more criteria, of which at least 2 are Major (96% sensitivity; 92% specificity)
Yamaguchi criteria for classification of adult Still’s disease
Presence of 5 or more criteria, of which at least 2 are Major (96% sensitivity; 92% specificity)
Major Criteria

  • Temperature of >39°C for >1 wk
  • Leukocytosis >10,000/mm3 with >80% PMNs
  • Typical rash
  • Arthralgias >2 wk

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The European Spondyloarthropathy Study Group (ESSG) Classification for Spondyloarthropathy (SpA)

According to the ESSG criteria, for a patient to be classified as having SpA, he or she has to satisfy one of two entry criteria: Inflammatory spinal pain OR synovitis that is either asymmetric or predominantly in the lower limbs.

  • Inflammatory back pain: Back pain is common among the general population. However, “inflammatory” back pain is much less common. Back pain is considered inflammatory if four of the following five criteria are found:

  1. Onset of back discomfort before the age of 40 years

  2. Insidious onset

  3. Persistence for at least three months

  4. Associated with morning stiffness

  5. Improvement with exercise

  • Asymmetrical synovitis: Asymmetrical synovitis, predominantly of the lower limbs is manifested by soft tissue swelling, warmth over a joint, joint effusion, and reductions in both active and passive range of motion. As with inflammatory spinal pain, the symptoms are worse after a period of rest.

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