Revised Criteria for Hereditary Non-Polyposis Colorectal Cancer (Lynch Syndrome)

Amsterdam Criteria (1991)

Three or more relatives with colorectal cancer, plus all of the following:

  • One affected patient should be a first-degree relative of the other two;

  • Colorectal cancer should involve at least two generations;

  • At least one case of colorectal cancer should have been diagnosed before the age of 50 years.

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Revised Criteria for the Diagnosis of Celiac Disease (CD) Proposed by the ESPGHAN

Definite diagnosis of CD

History and clinical presentation compatible with CD

  1. Serological screening compatible with CD: antigliadin antibody (AGA) antiendomysium antibody (AEA), tissue transglutaminase (tTG) antibody.
  2. Histological findings compatible with CD: villous atrophy
  3. Obvious clinical and serological response to a gluten free diet (GFD)
  4. Subject >2 years old
  5. Rule out other clinical conditions mimicking CD Continue reading

Revised ARA Criteria for the Classification of Rheumatoid Arthritis (RA)

For classification purposes, a patient is said to have RA if he or she has satisfied at least 4 of the following 7 criteria. Criteria 1 through 4 must have been present for at least 6 weeks. Patients with 2 clinical diagnoses are not excluded. Designation as classic, definite, or probable RA is not to be made.
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