Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a rare form of vasculitis. In this disorder, small-sized blood vessels in the nose, sinuses, ears, lungs and kidneys become inflamed and damaged. Continue reading
Three of the following five criteria were required to meet American College of Rheumatology (ACR) classification criteria for hypersensitivity vasculitis:
According to the ESSG criteria, for a patient to be classified as having SpA, he or she has to satisfy one of two entry criteria: Inflammatory spinal pain OR synovitis that is either asymmetric or predominantly in the lower limbs.
Inflammatory back pain: Back pain is common among the general population. However, “inflammatory” back pain is much less common. Back pain is considered inflammatory if four of the following five criteria are found:
Onset of back discomfort before the age of 40 years
Persistence for at least three months
Associated with morning stiffness
Improvement with exercise
Asymmetrical synovitis: Asymmetrical synovitis, predominantly of the lower limbs is manifested by soft tissue swelling, warmth over a joint, joint effusion, and reductions in both active and passive range of motion. As with inflammatory spinal pain, the symptoms are worse after a period of rest.
I. Ocular symptoms: a positive response to at least one of the following questions:
Have you had daily, persistent, troublesome dry eyes for more than 3 months?
Do you have a recurrent sensation of sand or gravel in the eyes?
Do you use tear substitutes more than 3 times a day?
1980 Criteria for the Classification of Systemic Sclerosis
The American College of Rheumatology (former American Rheumatism Association – ARA) has defined criteria, that are 97 % sensitive and 98 % specific for systemic sclerosis (SSc) as follows:
Proximal diffuse (truncal) sclerosis (skin tightness, thickening, non-pitting induration)
American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa (PAN). Classified as PAN if at least three of the 10 criteria are present:
ACR Classification Criteria for Osteoarthritis of the Hip
Hip pain plus at least two of the following:
ESR of less than 20 mm per hour
Femoral or acetabular osteophytes on radiographs
Joint space narrowing on radiographs
Primary (no other evident associated disease)
- Hereditary neutrophilia
- Chronic idiopathic neutrophilia
- Chronic myelogenous leukemia (CML) and other myeloproliferative diseases
- Familial myeloproliferative disease
- Congenital anomalies and leukemoid reaction
- Leukocyte adhesion deficiency (LAD)
- Familial cold urticaria and leukocytosis
- Postinfectious: varicella, measles, rubella, hepatitis A and B, mononucleosis, influenza, cytomegalovirus, parvovirus, acquired immunodeficiency syndrome (AIDS), S. aureus, brucellosis, tularemia, rickettsia, Mycobacterium tuberculosis, sepsis.
- Drug induced: Antineoplastic agents, procainamide, antithyroid drugs, sulphasalazine, phenothiazines, semisynthetic penicillins, nonsteroidal anti-inflammatory agents, aminopyrine derivatives, benzodiazepines, barbiturates, gold compounds, sulfonamides, propranolol, dipyridamole, digoxin, acetyldigoxin, sulfamethoxizole, anticonvulsants
- Benign familial neutropenia
- Chronic benign neutropenia of childhood
- Chronic idiopathic neutropenia
- Autoimmune neutropenia
- Isoimmune neutropenia
- Neutropenia associated with immunologic abnormalities
- Neutropenia associated with metabolic diseases
- Neutropenia due to increased margination
- Nutritional deficiency