The BODE is a multidimensional index designed to assess clinical risk in people with chronic obstructive pulmonary disease (COPD). It combines four important variables into a single score: (B) body mass index; (O) airflow obstruction measured by the forced expiratory volume in one second (FEV1); (D) dyspnoea measured by the modified Medical Research Council (MRC) scale; and (E) exercise capacity measured by the 6-minute walk distance (6MWD). Each component is graded and a score out of 10 is obtained, with higher scores indicating greater risk. The BODE index reflects the impact of both pulmonary and extrapulmonary factors on prognosis and survival in COPD.
|FEV1, % predicted||>/= 65||50–65||35–49||</= 35|
|6MWD, meters||>/= 350||250–349||150–249||</=149|
|BMI||> 21||</= 21|
FEV1 = forced expiratory volume in 1 second; MRC = Medical Research Council; 6MWD = 6-minute walk distance test; BMI = body mass index
Calculation of the BODE index. Points from each variable are added according to the threshold value measured for each one. The value ranges from 0 to a maximum of 10
Modified MRC Dyspnoea Scale
|0||Breathless only with strenuous exercise|
|1||Short of breath when hurrying on the level or walking up a slight hill|
|2||Slower than most people of the same age on the level because of breathlessness or have to stop for breath when walking at my own pace on the level|
|3||Stop for breath after walking about 100 meters or after a few minutes at my own pace on the level|
|4||Too breathless to leave the house or I am breathless when dressing|
- Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, Pinto Plata V, Cabral HJ. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med. 2004 Mar 4;350(10):1005-12. [Medline]
- Cote CG, Celli BR. BODE index: a new tool to stage and monitor progression of chronic obstructive pulmonary disease. Pneumonol Alergol Pol. 2009;77(3):305-13. [Medline]
Created Jun 28, 2011.